Cell cycle-dependence of HL-60 cell deformability
نویسندگان
چکیده
منابع مشابه
evaluation of effect of as2o3 on cell growth, cell cycle and apoptosis in human leukemia cell line hl-60
introduction : arsenic trioxide (as2o3) causes antitumor effects by various mechanisms, including degradation of pml-rara in the acute promyelocytic cells, growth inhibition and induction of apoptosis. however, the precise mechanisms of these processes remain incompletely understood. the purpose of this study was to evaluate the effects of arsenic trioxide on cell growth, cell cycle regulation ...
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Using rhodamine 123 to stain mitochondria of the human cell line HL-60, we have followed their increase over the cell cycle by flow cytometry. A near-linear synthesis of mitochondrial mass was shown to occur over the cell cycle. A comparison with the cell's DNA synthesis pattern obtained by the same technique established a common time-base. The mitochondrial synthesis curve changes with culture...
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The contribution of the metabolic state of human erythrocytes to maintenance of cellular deformability was studied during and after in vitro incubation in serum for periods up to 28 hr. An initial loss of membrane deformability became apparent between 4 and 6 hr when cellular adenosine triphosphate (ATP) levels were approximately 70% of initial values. Membrane deformability then remained stabl...
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Background: Neutrophils are the most abundant white blood cells in humans. Recently, a novel strategy called the formation neutrophil extracellular traps (NETs) was described. NETs is a new strategy for pathogen response. This study focused on whether LPS induced NETs release in vitro in the HL60 cell line. Methods: In this study, the HL60 cell line was used for culture and DMSO for induction ...
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Leukemia cells (HL-60) were induced to mature towards granulocytic and monocytic phenotypes using 1.1% dimethyl sulfoxide and 5 X 10(-7) M 1-beta-D-arabinofuranosylcytosine, respectively. Granulocytic maturation was accompanied by a slight decrease in cell volume and in total cell protein, but with an increase in acid phosphatase. DNA histograms showed that after 7 days there was a decrease in ...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1996
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(96)79768-0